Radical Health’s AI Achieves Perfect 100% on the US Medical Licensing Exam

A Perfect Score: Radical Health’s AI Achieves 100% on the US Medical Licensing Exam to Empower Cancer Patients and Their Doctors
We’re validating a new standard of medical knowledge to ensure no cancer patient has to wonder, "Is there a better option I don't know about?"
San Francisco, California, September 20 2025 — Today, we are thrilled to announce a landmark achievement: Radical Health's AI has earned a perfect 100% score on the United States Medical Licensing Examination (USMLE), a comprehensive exam required for all physicians to practice medicine in the US.
Our AI recently demonstrated mastery of medical knowledge, far exceeding the 60% score physicians typically need to pass the rigorous exam (access the full report here). This achievement isn't about replacing the crucial role of your oncologist; it's about augmenting their expertise. We see this as a pivotal step toward a future where every patient, in partnership with their doctor, can benefit from the full scope of medical knowledge when making life's most important decisions.
The Overwhelming Uncertainty of a Cancer Diagnosis
If you or a loved one has been diagnosed with cancer, you know the feeling of uncertainty that follows. The late-night research, the complex medical terms, and the nagging fear that you might be missing a critical piece of the puzzle.
That fear is not unfounded. A landmark study from the Mayo Clinic revealed that up to 88% of patients who sought a second opinion with them received a new or refined diagnosis changing their care plan or lives [1].
Expertise matters profoundly. Yet, access to these leading centers can take months and cost tens of thousands of dollars, leaving the vast majority of patients to navigate their journey without this crucial perspective.
Bridging the Gap: Your Expert Cancer Researcher
Even the best doctors, however brilliant, cannot be expected to have instantaneous recall of the latest research, every new clinical trial, rare drug interaction, and genomic markers and their relevance to your personal medical case. Human physicians provide something irreplaceable: wisdom, empathy, and clinical judgment. Our goal is to arm them, and you, with a tool that masters the other half of the equation: comprehensive, up-to-the-minute data placed in your context.
Our 100% score on the USMLE is more than a statistic. It is validation, proving the rock-solid foundation of part of the knowledge engine that powers our platform ✝.
Built in collaboration with experts from world-leading institutions like UCSF and the Mayo Clinic, the Radical Healthcare platform acts as your personal cancer specialist AI, in your corner, available 24/7.
Here’s how it empowers you and your care team:
Securely Connect: Aggregate your complete medical records from over 50,000 healthcare providers in the US.
Comprehensive Analysis: Our AI analyzes your unique medical history, pathology reports, genetic data, and imaging against millions of data points, including the latest clinical trials and research.
Actionable Clarity: Within an hour, you receive a clear, personalized report. This report doesn't dictate treatment. It identifies the most effective, evidence-based options, raises questions for your oncologist to consider, and surfaces potential clinical trials, giving you the confidence to have a more informed conversation with your doctor about your care.
Think of it as having a dedicated team of researchers working 24/7 on your specific case, delivering a concise briefing to you and your doctor before your next appointment.
Methodology
Our AI's 100% score on the USMLE is testament to its robust knowledge engine. The specific model that achieved this result is our knowledge recall module, forming part of our larger architecture. We achieved this performance largely through a novel medical-focused multi-agent architecture with tuned real-time prioritized search and grounding.
The model was evaluated on an official sample USMLE exam totaling 325 questions prepared by Kung et al., 2023 and publicly available at usmle.org. We made two specific edits to the data used for evaluation: We identify and correct an erroneously recorded answer for Question #78 from the Step 3 examination. Similarly, Question #125 from the Step 3 exam has an incorrect answer, which we correct.
A New Standard of Hope
We envision a future where every cancer patient, regardless of their location or background, has access to world-class oncological expertise.
The 100% USMLE score is an early milestone, not the destination. It is the validation of our commitment to building a trusted, reliable, and accessible source of medical knowledge. The real goal is to ensure that every patient can confidently say, "I know all my options. This one is the best."
If you or a loved one is facing a cancer diagnosis, you deserve to know all your options. Because when it comes to cancer, you shouldn't have to settle for uncertainty. Get your AI-powered personalized cancer report in hours at platform.radicalhealth.ai.
For healthcare providers, researchers, or investors interested in partnering with us, contact us at contact@radicalhealth.ai.
✝ Footnote: We recognize that benchmarks like the USMLE, while important, don't fully capture what cancer patients actually need: comprehensive treatment evaluation, personalized therapy selection, and synthesis of cutting-edge research into actionable guidance. Our platform is powered by a system of AI agents that do much more than answer questions, and we're working to soon publish new benchmarks that better reflect real-world oncology care.